Bachelor’s disseration: Adaptive Kernel Methods for Sequence Classification in Bioinformatics

I wrote my Bachelor thesis in 2009/2010 in Duisburg, supervised by Prof. Hoffmann, Bioinformatics, Essen, and Prof. Pauli, Intelligent systems, Duisburg.

The work is about classification of amino acid sequences using SVM and string kernels. In particular, I compared the Distant Segments kernel by S├ębastian Boisvert to a standard Spectrum kernel on a HIV dataset. In addition, I described a bisection based method to search for the soft-margin parameter of the underlying SVM, which outperformed a standard grid-search.